Using CRISPR to silence the E6 gene in Human Papilloma Virus, Duke researchers were able to re-start the cervical carcinoma cell's natural self-destruct mechanisms, including the gene p53. Similar results were obtained against the HPV-E7 gene, turning on … "This method has the potential to be a single hit treatment that will dramatically reduce tumor load without having any effect on normal cells." The researchers are also targeting other viruses that use DNA as …

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Editing HPV's genes to kill cervical cancer cells | Science Codex